Descriere - Comprehensive Medicinal Chemistry II, Eight-Volume Set Volume 1-8

 Comprehensively reviews - the strategies, technologies, principles and applications of modern medicinal chemistry
 Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets
 Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs
Related Titles

* Comprehensive Organic Functional Group Transformations II, 2nd Edition : A Comprehensive Review of the Synthetic Literature 1995 - 2003

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Online via ScienceDirect - Online via ScienceDirect

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Description

The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well.

Also available online via ScienceDirect (2006) – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com.

Readership

New and experienced scientists of all disciplines concerned with drug research in both academia and industry, including medicinal chemists, organic chemists, biochemists, biologists, and pharmacologists; students, scientists teaching medicinal chemistry; researchers and executives in the pharmaceutical and biotechnology industry.
Quotes

qu:About the first edition
"Beautifully produced six-part magnum opus of medicinal chemistry. Comprehensive and remarkably up-to-date. The preface boasts a milestone in the literature of the subject in terms of coverage, clarity and presentation' with which I agree." source:The LANCET @qu: "A most impressive collection of up to date, excellently referenced reviews covering virtually every aspect of biological science of relevance to the production of medicines.source:CHEMISTRY IN BRITAIN

Table of Contents

Volume 1 Global Perspective (P. Kennewell).
Volume 2 Research and Development (W.H. Moos).
Volume 3 Technologies (H. Kubinyi).
Volume 4 Computer-Assisted Drug Design (J.S. Mason).
Volume 5 ADME-Tox Approaches (B. Testa and H. van de Waterbeemd).
Volume 6 Therapeutic Areas I (M. Williams).
Volume 7 Therapeutic Areas II (J. Plattner and M.C. Desai).
Volume 8 Case Histories and Cumulative Subject Index (J.B. Taylor and D.J. Triggle).

Editura:  Academic Press
Anul: 2007
Pagini: 7200